Project Description
Charlotte Dessaux
Early Stage Researcher 4,
CSIC
Project Title and Work Package(s): Role of the L. monocytogenes stressosome during intracellular pathogenesis (WP2, WP3, WP5)
Objectives: To: (1) determine the role played stressosome components in the invasion and intracellular life cycle of L. monocytogenes; (2) measure the influence of the stress sensing via the stressosome on the L. monocytogenes proteome in the vacuole and cytoplasm of the host cell; (3) Determine the influence of the stressosome on the cell envelope structure of L. monocytogenes (protein and glycolipid).
Expected Results: A comprehensive understanding of the role of stress sensing via the stressosome on the intracellular behaviour of L. monocytogenes. A full description of the role of the stressosome in regulating the proteome and cell surface properties during the intracellular stage of infections.
Personal Statement
I come from France where I have been graduated in Master 2 Structural and Functional Biochemistry at Université Paul Sabatier Toulouse (June 2017). I did master internships at The Institute of Pharmacology and Structural Biology (Toulouse) where I studied the role and the structure-function relationships of mycobacterial cell envelope lipids and the stimulation of CD1-restricted T cells. Since September 2017, I joined Centro Nacional de Biotecnología-CSIC in Madrid in order to investigate the role of Listeria monocytogenes during intracellular pathogenesis.
Congratulations Dr Charlotte Dessaux!!
Congratulations to Charlotte Dessaux who successfully defended her PhD thesis on October 22nd 2020. Charlotte ESR 4 on the PATHSENSE project worked on her PhD project at CSIC/CNB in Spain since September 2017 . Read
My secondment in AquilaBioscience in Galway
The PathSense network gives us the opportunity to do secondments during the PhD. I did the first one in AquilaBioscience, National University of Ireland, Galway, under the supervision of Dr Marta Utratna. This spin-out company