9. Emilija Ivanova

Project Title and Work Package(s): Identification and characterisation of novel antimicrobial plant extracts using stress-sensing biosensors (WP5)

Objectives: To: (1) exploit the stress-sensing biosensors generated by participants UC and NUIG to screen plant extracts and an existing compound library for antimicrobial activity against L. monocytogenes and B. subtilis; (2) extract, purify and chemically characterise novel plant compounds that have antimicrobial activity; (3) characterise the effects of the newly isolated antimicrobial compounds on cell physiology and virulence in collaboration with CSIC; (4) examine the effectiveness of the novel antimicrobials in food trials.

Expected Results: Development of a new stress-sensing biosensor screen for antimicrobial compounds. Isolation of novel antimicrobial plant extracts and characterisation of their effects on bacterial cells. Validation of the new antimicrobial compounds in a food trial.

Personal Statement

Hi! My name is Emilija, I come from Skopje, Macedonia and I have a Master of Science in Biochemistry/Physiology with a minor in Microbiology. I’ve always had a great interest in bioactive compounds: their isolation, identification and purification, elucidating their mode-of-action and identifying their molecular targets. Bioactive molecules are not only the answer to various human ailments and diseases, but nowadays their use has become irreplaceable in various industrial processes.