12. Manisha Pandey

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12. Manisha Pandey2019-07-29T13:47:12+00:00

Project Description

Manisha Pandy

Manisha Pandey

Early Stage Researcher 12,
University of Dundee

Project Title and Work Package(s): Genetic study of the molecular mechanisms of sensory perception in B. subtilis. (WP 4)

Objectives: To: (1) generate σB reporter fusions that allow the quantification of stressosome-dependent stress sensing in B subtilis; (2) Use random transposon mutagenesis and targeted mutagenesis of RsbR and its paralogues to identify mutants with defective stress sensing (either locked-on or blind); (3) develop single-cell and population based mathematical models that account for the stress sensing behaviour of B. subtilis in collaboration with participant #UC.

Expected Results: The development of stress-sensing biosensors for B. subtilis, which will be available to the Network. Identification of novel factors influencing stressosome-mediated sensing in B. subtilis and a genetic definition of residues important for sensing in RsbR and its paralogues. A model describing the molecular mechanisms of stress sensing in Bacillus.

Personal Statement

I am Manisha Pandey from the land of Taj Mahal and Mars orbital Mission – India. I did my Bachelor’s in Zoology(h) from University of Delhi, India and my Master’s in Life Sciences from Jawaharlal Nehru University, India.

In my master’s dissertation I worked on a protein  involved in the phagocytic process of pathogen Entamoeba histolytica. Later, I briefly  worked in a lab working on chondrogenic differentiation of human bone marrow Mesenchymal Stem Cells.

I am currently recruited as an ESR in University of Dundee. My primary interest are infection biology and development biology. Apart from science, I like interacting with new people, going on nature walks, reading, swimming and pondering over the unity and diversity of life.

Manisha has left the PATHSENSE programme.

2103, 2018

Save your Pizza!

By |March 21st, 2018|

“What you see is that the most outstanding feature of life's history is a constant domination by bacteria.” – Stephen Jay Gould   I am Manisha Pandey and I am one of the lucky ones

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