5. Torkel Loman

5. Torkel Loman 2017-12-20T14:44:36+00:00

Project Description

Torkel Loman

Torkel Loman

 

Early Stage Researcher 5,
University of Cambridge

Project Title and Work Package(s): Modeling the sensory behaviour of B. subtilis and L. monocytogenes in response to food-related stresses (WP4, WP5)

Objectives: To: (1) Perform a single cell time lapse microscopy on B. subtilis cells carrying a fluorescent reporter of σB activity and measure σB activity in response to acid pH, osmotic stress and ethanol; (2) measure the effects of stressosome mutants with impaired sensing ability on the activation of σB a single cell level; (3) produce a mathematical model describing the sensory behaviour of B. subtilis and test this in a food-related setting.

Expected Results: A detailed understanding of how stressosome-mediated stress sensing and signal transduction influences the σB activation in B. subtilis in response to acid, salt and ethanol. A mathematical model that predicts the sensory behaviour of bacteria that will be validated in a food-related setting.

Personal Statement

Previously I’ve studied applied mathematics and biology in Lund, Sweden. My research interest is the application of mathematics, mainly in biology.

1911, 2018

Modelling Biochemical Reactions

By | November 19th, 2018|

I spend most of my time modelling biochemical reaction networks, these are typically signal transduction systems. As a cell senses some change in its environment it usually want to respond in some way, this could

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